In summary, the Taq1B CETP polymorphism was significantly associated with HDLc levels and the presence of T2D and, although we did not find the same association between the -250A/G LIPC polymorphism and HDLc levels or T2D, the presence of the A allele appears to exert a protective effect in B1B1 genotype carriers in our population. This evidence concerns the gene CETP and type 2 diabetes mellitus.