Towards this goal, we examined the utility of the selective sGC inhibitor 1H-[1], [2], [4] oxadiazolo-[4,3-a]quinoxalin-1-one (ODQ) [19], [20] in reversing biochemical, electrophysiological, histochemical, and behavioral correlates of experimental PD observed in 6-OHDA-lesioned rats and mice chronically treated with MPTP. Here, SGCB is linked to Parkinson disease.