Provided the expression of prochemerin in lung [28], [29], its processing by neutrophil proteases, the preferential expression of ChemR23 by pDCs, and the role of pDCs and neutrophils in the physiopathology of viral infections of the lung, we investigated the potential involvement of the chemerin-ChemR23 system in pDC recruitment and its functional consequences during viral pneumonia. The gene discussed is CMKLR1; the disease is viral infectious disease.