At the downstream end of this path, cytochrome p450 enzymes (MYP19A1, CYP2B6 and CYP1B1) act on AA and LA as substrates to form diverse epoxyeicosatrienoic acids (EET), hydroxyeicosatrienoic acids (HETE) and epoxyoctadecenoic acids (EpOME), involved in the resolution of inflammation with subsequent relevance to cardiovascular disease [22], [23]. Here, CYP1B1 is linked to cardiovascular disorder.