The average optical density of IGF-1R in low-differentiated ovarian cancer samples was 0.455 ± 0.049, which was significantly higher than the optical densities measured in moderate- (0.413 ± 0.038) (P < 0.05) and high-differentiation samples (0.412 ± 0.052) (P < 0.05). The gene discussed is IGF1R; the disease is ovarian cancer.