SMARCA5 and dermatomyositis: When Drosophila ISWI and CHD1 as well as human Snf2H, Brg1 and Mi-2 (dermatomyositis specific autoantigen Mi-2) were tested side by side in an in vitro sliding assay, each remodeler moved the nucleosome to different positions although the underlying DNA sequence was the same in all cases [34].