HBL6, L540 and Raji cells were highly sensitive to the IT with IC50 values ranging from 2 to 13 × 10−12 M and concentration causing 100% of protein synthesis inhibition (IC100) at 10−10 M. CD38+ neoplastic cells obtained from a NHL patient were completely eliminated with 10−8 M IT. This evidence concerns the gene CD38 and non-Hodgkin lymphoma.