Recently [156], in vivo CED of magnetic nanospheres conjugated to an antibody that selectively binds to the epidermal growth factor receptor (EGFR) mutant (EGFRvIII) found on glioblastoma xenografts, not only allowed specific tumor visualization on MRI, but through an apoptotic mechanism, was associated with targeted cell death with sparing of normal astrocytes. The gene discussed is EGFR; the disease is glioblastoma.