Cervical cancers are the second most common cancers in women and since EGFR is found over-expressed in almost 90% of cervical tumors, targeting these receptors seems a promising approach: a combination of EGF-saporin SE fusion toxin with saponins resulted in a drastic enhancement of cytotoxicity ranging from 9,000-fold to 2,500,000-fold, again depending on the cell lines analyzed. Here, EGFR is linked to cervical carcinoma.