PRRT2 and cancer: Although PKC mutations are very uncommon in human cancers, the expression of various PKCs, including PKCδ, is often altered in human cancers, as illustrated by the data summarized in Table 2 [12,13,14,15,16,17,18,19,20,21,22,23,24,25,26,27,28,29,30,31,32,33,34,35,36].