HLA-DRB1 and type 1 diabetes mellitus: The minor T allele is in linkage disequilibrium with HLA-DQB1*06, HLA-DQB1*05, HLA-DRB1*15 and HLA-DRB1*01 (r2 = 0.48, 0.28, 0.27 and 0.19, respectively) which are known to confer reduced risk of T1D, specifically the HLA-DRB1*15-HLA-DQB1*06 haplotype (Table S2) 27.