NPPB and cancer: In recent years, several studies have suggested the use of BNP as a screening test for asymptomatic LV dysfunction (Latour-Pérez et al, 2006; Romano et al, 2009), and some authors have reported conflicting results regarding the value of BNP and NT-proBNP in cancer patients undergoing chemotherapy (Bauch et al, 1992; Suzuki et al, 1998; Meinardi et al, 2001, 2002; Sandri et al, 2005; Germanakis et al, 2006; Kouloubinis et al, 2007).