TNF and rheumatoid arthritis: In this context, there are several targets for the treatment of inflammation and inhibition of pro-inflammatory cytokines, like the tumor necrosis factor alpha (TNF-α) and interleukins (IL-6 and IL-1β), that can be used for the treatment of rheumatoid arthritis, inflammatory intestinal diseases, medulla transplant-related rejection problems [36] and inflammatory diseases on the respiratory level [37].