The 2q35 SNP rs13387042 demonstrated significantly stronger associations with PR-positive than PR-negative breast cancer for both BRCA1 and BRCA2 mutation carriers (P = 0.034 and P = 0.0086, for PR-positive for BRCA1 and BRCA2 respectively), suggesting this SNP may be more relevant for BRCA1 and BRCA2 tumours expressing PR. This evidence concerns the gene BRCA1 and neoplasm.