Beta-catenin expression in metastatic SLN(s) was significantly different for age (P < 0.001), type of tumor (P < 0.001), tumor cell differentiation (P < 0.001), tumor invasion depth (P < 0.001), lymph node metastasis (P = 0.003), liver metastasis (P < 0.001) and TNM stage (P < 0.001) (Table 2). This evidence concerns the gene CTNNB1 and neoplasm.