EBF1 and acute lymphoblastic leukemia: In a cohort of 45 adolescent and adult ALL cases, deletions in EBF1 were observed in 4.4% of cases; in relapsed children, EBF1 deletions are particularly frequent (25%), suggesting a possible contribution of this TF for the development of relapse and a potential prognostic value [65, 66, 97, 99].