Anemia in monkeys with CIA is characterized by decreased serum iron and transferrin (Tf)-saturation, and by elevated serum ferritin, and its severity is correlated with serum IL-6 levels; therefore, anemia in monkeys with CIA is very similar to human anemia in inflammatory diseases, at least with respect to the changes in serum parameters [7]. The gene discussed is TF; the disease is anemia (phenotype).