TGFB1 and diabetes mellitus: A recent study demonstrated that islet-specific Treg induced from the BDC-6.9 TCR transgenic mouse by activation of T cells in the presence of TGF-β could suppress both spontaneous diabetes as well as transfer of diabetes into NODscid mice by diabetic NOD spleen cells or activated BDC-2.5 TCR transgenic Th1 effector T cells [155].