Consistent with studies reporting regulation of Fas (CD95) expression via the Ras-ERK pathway [56], [57], [58] Fas expression was elevated in WT cortical NPC treated with PIC (n = 12; Mann-Whitney U, p = 0.02; relative to PBS-treated WT control group; Fig. 7b, d, f). This evidence concerns the gene FAS and nasopharyngeal carcinoma.