Whereas in our pathway analysis (as shown in Table 2), more genes are identified as part of Type I diabetes mellitus and Allograft rejection pathways (i.e. CD28, HLA-B, HLA-C, HLA-DMB, HLA-DPA1, HLA-DQA2, HLA-DRA, IL12A). The gene discussed is CD28; the disease is type 1 diabetes mellitus.