Most of these pathways (Chemokine signaling, Neurotrophin signaling, Pathways in cancer, Leukocyte transendothelial migration, T cell receptor signaling, Toll-like receptor signaling, Allograft rejection, MAPK signaling, Apoptosis, Jak-STAT signaling) have been previously found to be associated with RA experimentally. The gene discussed is SOAT1; the disease is rheumatoid arthritis.