A large percentage of these cells stained positively for GP-BAR1 and the phenotypic characterization of LPMC in the TNBS colitis demonstrates that a ≈90% of CD14+ cells were GP-BAR1 positive, while only a small proportion of CD3+ cells expressed the receptor strongly indicating a role for GP-BAR1 in regulating cells of innate immunity. The gene discussed is GPBAR1; the disease is colitis.