Interestingly, the only other signature showing such a strong enrichment of cancer related KEGG pathways was that of Sotiriou et al., whereas the signature by Bertucci et al. showed a much weaker enrichment (“ErbB signaling”, “Pathways in cancer”, “Adheres junction” with FDR<0.05) and the others revealed no enrichment at FDR cutoff 5%. Here, EGFR is linked to cancer.