To determine the ability of transgenic CD8 T cells to proliferate in vivo in response to MCMV infection, we adoptively transferred 105 Mini or 104 Maxi CD8 T cells into C57BL/6 mice one day prior to infection and compared endogenous and transgenic M38-specific CD8 T cell responses in the blood at different time points after infection (Fig. 2C). The gene discussed is CD8A; the disease is infection.