MYC and neoplasm: This cluster of miRNAs was reported to have potential oncogenetic function in various tumours, with its elevation either being caused by genome amplification or by transcriptional activation by MYC (Woods et al, 2007); therefore, we hypothesised that plasma miRNAs, which are located in the miR-17–92 cluster, might be a potentially useful biomarker in patients with pancreatic cancer.