Serial sections of each tumor in the isotype-treated, α-TEA, trastuzumab and α-TEA+trastuzumab treatment groups were histochemically stained with hematoxylin & eosin (H&E), analyzed for apoptosis by TUNEL assay (Figure 6A and 6B) or immunostained with Ki-67-specific antibody (Figure 6C and 6D). Here, MKI67 is linked to neoplasm.