CD4 and pulmonary tuberculosis: A sub-study from this trial [15], presented at the 2011 CROI concluded that among patients with pulmonary TB with a CD4 T-cell count <50 cells/μL, cART initiation within 4 weeks was associated with improved AIDS-free survival, but a higher risk of IRIS; for patients with a CD4+ T-cell count >50 cells/mm3 earlier cART initiation was associated with a reduction in the risk of IRIS without compromising AIDS-free survival.