A number of factors in this list are clearly antiviral, but several could also be defined as facilitators of infection, such as AGFG1, AP2B1, CUL5, HIVEP1, IPO7, KPNA1, KPNA5, KPNA6, KPNB1, PML, SMAD3, SMAD4, SP1, SUPT4H1, TAF8, TOP1, XRCC6. The gene discussed is CUL5; the disease is infection.