In addition to TP73 and PRDM16, recently shown to be rearranged with various partner genes in myeloid as well as lymphoid malignancies (Duhoux FP et al, submitted manuscript), we identified 3 other interesting genes, likely involved in the pathogenesis of hematological malignancies: PRKCZ, RERE and AJAP1. PRKCZ and RERE were the only genes at the 1p36 breakpoint in 2 CLL patients, respectively in a t(1;4)(p36;q25) (case 015) and in an isolated t(1;13)(p36;q13) (case 014). The gene discussed is PRDM16; the disease is B-cell chronic lymphocytic leukemia.