MYC and lymphoma: When P493-6 B cell-specific Myc target genes were used for analysis of mouse gene expression from wild type, premalignant Myc or malignant Myc B cells, the vast majority (15 out of 18, or 83.3%) of the B cell specific Myc-induced genes increased in this transgenic lymphoma model (Figure 6C) while 73.9% (17 out of 23) repressed genes were decreased (Figure S4).