In colorectal cancer, only KRAS mutation was identified as an independent indicator for poor OS from time of diagnosis and metastasis (HR: 13.56, 95% CI 1.61–113.88, p = 0.016 and HR: 5.46, 95% CI 1.07–27.89, p = 0.04 respectively). This evidence concerns the gene KRAS and colorectal cancer.