NRAS and melanoma: NRAS mutation and male gender were the only independent factors associated with shorter OS from time of diagnosis (Hazard ratio (HR): 2.52, 95%CI 1.32–4.80, p = 0.005 and HR: 2.84, 95%CI 1.46–5.53, p = 0.002, respectively) whereas diagnosis of melanoma predicted a better OS from time of diagnosis (HR: 0.15, 95%CI 0.04–0.58, p = 0.005).