The expression of FBP1 was dramatically downregulated in 66.7% (6/9) human liver cancer cell lines including HepG2, BEL-7402, SMMC-7721, Sk-Hep1, MHCC-97H and MHCC-97L (Figure 1A) when compared to human normal liver cells Lo2. Here, FBP1 is linked to liver cancer.