Both of these two exons are located in the 5' UTR of ADNP, suggesting that this gene fusion may encode for a truncated version of C20orf132. ADNP encodes for an activity-independent neuroprotector homeobox protein that has been found to be involved in cell survival, due to its proximity to a region that is frequently amplified in cancer, 20q12-13.2 [40]. This evidence concerns the gene ADNP and cancer.