Finally, flow cytometry of 3 representative colorectal carcinoma cell lines provided evidence that at least some of the denatured HLA-A and HLA-E molecules detected by HCA2 and MEM-E/02 on archival tissues derive from native molecules that are co-expressed on the surface of live cells (Additional file 1, Fig. S2). The gene discussed is HLA-A; the disease is colorectal carcinoma.