The vascular adhesion molecule VCAM-1 mediates leukocyte rolling and adhesion to endothelium during VCAM-1-dependent eosinophil infiltration into the lung in experimental ovalbumin-induced asthma [2], as well as T-cell infiltration across the blood-brain barrier in experimental allergic encephalomyelitis [3]. This evidence concerns the gene VCAM1 and asthma.