CCL5 and Nasal polyposis: Similarly, Yoshifuku et al.24observed the effect of TNF-α and IL-4 on the expression of eotaxin, RANTES and VCAM-1 in nasal polyp fibroblast using ELISA and demonstrated that TNF-α at the dose of 10 ng/mL for 24 hours was able to induce the secretion of RANTES and VCAM-1, but not of eotaxin.