To date, several new candidate cancer-susceptible genes have been cloned to 8p22, such as deleted in breast cancer 2 (DBC2), leucine zipper tumor suppressor 1 (LZTS1), deleted in liver cancer 1 (DLC1), and mitochondrial tumor suppressor 1 (MTUS1) [49–52]. The gene discussed is LZTS1; the disease is cancer.