Furthermore, the mean tumor volume in the LZAP overexpressed group at the end of observation was significantly smaller than that of the control group (49.37 mm3 vs. 743.57 mm3 for HepG2, 74.48 mm3 vs. 464.81 mm3 for sk-Hep1; Fig. 7A and B). The gene discussed is CDK5RAP3; the disease is neoplasm.