SNAI2 and breast cancer: To obtain a global view of the genome-wide impact of Snail or Slug expression in a luminal breast cancer cell model (MCF-7), we isolated RNA from MCF-7 cells 0,1, 2 and 4 days following infection with control, Snail or Slug adenovirus (figures 1A and D) and examined transcriptome changes using Affymetrix arrays.