Interestingly, and in contrast to LBP, ApoE and SAA which are elevated in serum of malaria patient, gelsolin was only found in serum from healthy individuals and disappeared in the malaria samples (Figure S1), suggesting that disappearance of normal serum proteins during malaria could be advantageous to include in biomarker profile related to malaria infection, since this reflects the pathological condition. The gene discussed is GSN; the disease is malaria.