Following cerebral ischemia, a cascade of inflammatory mediators including cytokines (TNF, IL-1α, IL-1β, IL-6, IL-10, TGFβ1) and chemokines (MCP-1 [CCL2], Mip-1α [CCL3], RANTES [CCL5]) is initiated. The gene discussed is CCL3; the disease is Cerebral ischemia.