Animals of this genotype displayed no ataxia or growth defects, and no cell death was detected in any region of the brain, including the cerebellar GCL, compared to littermates that did not contain the Oxr1 transgene (bel/bel; Tg(CAG-Oxr1)−/−) (Figure 3B). Here, OXR1 is linked to cerebellar ataxia.