Based on these tests, it was suggested that EBV-specific T cells from SLE patients might have impaired IFN-γ secreting capacity.[20] The latter study was however hampered by limitations in cohort size, and by the fact that function and frequency of EBV-specific CD8+ T cells were not monitored simultaneously at the single cell level. The gene discussed is IFNG; the disease is systemic lupus erythematosus.