The LRP1 is a multifunctional receptor that is expressed in a wide range of tissues, as well as in multiple malignancies, including colon cancer, renal cancer, and melanocytic tumours (de Vries et al, 1996; Desrosiers et al, 2006; Obermeyer et al, 2007). This evidence concerns the gene LRP1 and malignant colon neoplasm.