TIA-1, a marker of stress granules that colocalizes with TDP-43 inclusions in frontotemporal lobar degeneration (FTLD-U) and ALS [28], is also upregulated (FC = 1.4, qSAM = 0%, pLIMMA < 0.005, qLIMMA~10%; Additional File 1. The gene discussed is TARDBP; the disease is amyotrophic lateral sclerosis.