In one South Indian consanguineous family an underlying recessive frameshift mutation in LTBP2 predicted to replace the terminal six amino acids of the protein with 27 novel amino acids (p.H1816PfsX28) was associated with the phenotype, which did not include glaucoma at the time of the study in any of the three affected siblings (10, 18, and 21 years of age) [15]. Here, LTBP2 is linked to glaucoma.