Ferrazzo and al. demonstrated in adenoid cystic carcinoma of salivary glands, that cyclin D1 expression was correlated with cytoplasmatic and nuclear galectin-3 expression, what could suggests that galectin-3 may play a role in cellular activation through cyclin D1 activation, but these authors observed in adenoid cystic carcinomas predominately nuclear galectin-3 expression [28]. The gene discussed is CCND1; the disease is adenoid cystic carcinoma.