Gene expression profiling revealed that Mmp10 is commonly overexpressed in many forms of human cancer, including lung, head and neck, esophageal, bladder, skin, colorectal, breast, cervical, nasopharyngeal, tongue and pancreatic cancers (Figure 5C and Table 5), suggesting a widespread role for Mmp10 in human malignancy. This evidence concerns the gene MMP10 and cancer.