Positive HURP expression was associated with the emergence and recurrence of transitional cell carcinoma [12], [13]; gene expression analysis revealed that HURP represented a prognosis marker capable of distinguishing between benign and malignant adrenocortical tumors [14], [15]; and in 293T cell lines (American Type Culture Collection (ATCC) Manassas, VA, USA), overexpression of HURP in differentiated cells increased cell growth and blocked apoptosis that is normally induced by serum starvation [16]. Here, DLGAP5 is linked to adrenal cortex neoplasm.