Due to X skewing might affect the interpretation of data in female, we disregard TLR7 SNP heterozygous females from analysis [15] and got a significant difference in homozygous TLR7 IVS2-151genotypes among controls and hepatitis C female patients (p = 0.021; OR = 8.55,95% CI = 0.99 to 73.4). This evidence concerns the gene TLR7 and hepatitis C virus infection.