Our data are in agreement with studies on adipocytes differentiated from mesenchymal stem cells where Dex did not alter gene or protein expression, but decreased AMPK activity [30] and with obervations in adipose tissue fom patients with Cushing's syndrome, where AMPK phosporylation is decreased [31]. Here, PRKAA2 is linked to Cushing syndrome due to macronodular adrenal hyperplasia.